Is it ok to take Antihistamine before Surgery?

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If you have a scheduled surgery in the near future, you may be wondering whether it’s safe to take antihistamines before your procedure. Antihistamines are commonly used to treat allergies and can help alleviate symptoms such as runny nose, sneezing, and itching. However, these medications can have side effects and may interact with anesthesia, which is used during surgery. In this blog post, we’ll explore the safety of taking antihistamines before surgery and provide you with all the information you need to make an informed decision.

Is it ok to take Antihistamine before Surgery?

Antihistamines and Anesthesia: Potential Risks

One of the main concerns with taking antihistamines before surgery is the potential for interaction with anesthesia. Antihistamines can cause drowsiness and sedation, and when combined with anesthesia, these effects can be intensified. This can lead to complications during surgery, such as a drop in blood pressure, slowed breathing, and delayed recovery from anesthesia. For this reason, many doctors recommend that patients avoid taking antihistamines for a period of time before surgery.

Another potential risk of taking antihistamines before surgery is the possibility of an allergic reaction. While antihistamines are used to treat allergies, they can also cause an allergic reaction in some people. This can be especially dangerous during surgery, as the stress on the body can exacerbate the allergic reaction and make it more difficult to manage. If you have a history of allergic reactions to antihistamines or any other medications, it’s important to let your doctor know before your surgery.

Antihistamines and Surgery: When to Stop Taking Them

If you’re taking antihistamines for allergies or any other condition, it’s important to talk to your doctor before your surgery. Your doctor can advise you on whether it’s safe to continue taking antihistamines leading up to your procedure. In general, it’s recommended that patients stop taking antihistamines at least 48 hours before surgery to minimize the risk of complications.

However, the specific timing and duration of when to stop taking antihistamines may vary depending on the type of surgery you’re having and the type of anesthesia that will be used. Your doctor may also take into account other factors, such as your overall health and any other medications you’re taking. It’s important to follow your doctor’s instructions closely and not make any changes to your medication regimen without consulting them first.

Alternative Options for Managing Allergies Before Surgery

If you’re concerned about stopping your antihistamines before surgery and experiencing allergy symptoms, there are other options available to manage your allergies. Your doctor may recommend other medications, such as nasal sprays or eye drops, that are safe to take before surgery. They may also suggest other strategies for managing your allergies, such as avoiding triggers or using a humidifier.

In some cases, your doctor may also recommend postponing your surgery if your allergy symptoms are severe or if you’re at a higher risk of complications due to your allergies. While this may be inconvenient, it’s important to prioritize your health and safety during the surgery.


In conclusion, while antihistamines are a common medication used to treat allergies, they can have potential risks and interactions with anesthesia during surgery. It’s important to talk to your doctor before your surgery about whether it’s safe to continue taking antihistamines and when to stop taking them. Your doctor can also recommend alternative options for managing your allergies before surgery, such as other medications or lifestyle changes. By following your doctor’s instructions and prioritizing your health, you can help ensure a safe and successful surgery.

Is it ok to take Antihistamine before Surgery?
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